EVIDENCE & RESEARCH

THE LONGEVITY JOURNAL.

Clinical whitepapers, centenarian biological mechanisms, and dietary protocols written by our scientific board.

Featured Whitepaper
FEATURED WHITEPAPER

The Cellular Architecture of Centenarians: What 100-Year-Old Blood Biomarkers Reveal

An in-depth analysis of cellular senescence, NAD+ regeneration, and dietary polyphenols observed across Okinawa and Sardinia.

BY DR. ELENA VANCE • 8 MIN READ MAY 2026
Article 2
NEUROLOGY

Polyphenols & Synaptic Plasticity in Middle Age

How bacosides and flavanols stimulate BDNF growth factors and protect against cognitive fatigue.

5 MIN READ • DR. KENJI TANAKA
Article 3
LONGEVITY HABITS

Ikigai: The Neurobiology of Purpose and Stress Reduction

Why having a daily sense of direction lowers resting cortisol and improves cardiovascular resilience.

6 MIN READ • SARAH JENKINS, MS
Article 4
CIRCADIAN REST

Restorative Sleep Habits of Okinawan Centenarians

Evening herbal infusions, darkness protocols, and deep slow-wave sleep architecture.

4 MIN READ • PROF. MARCO MORETTI