BLUE METABOLIC
HPLC Verified ✓
100% Bio-Identical
PROTOCOL SIZE 60 Gastro-Resistant Capsules
FORMULATION SKU BZ-MET-004
Metabolic Health — SCIENTIFIC DOSSIER

BLUE METABOLIC

AMPK Activator & Fasting Mimetic

Cellular metabolic modulator mimicking the benefits of caloric restriction and intermittent fasting through direct AMPK pathway activation.

BIOLOGICAL LONGEVITY FOUNDATION

BLUE METABOLIC is designed around the AMPK (AMP-Activated Protein Kinase) signaling axis — the master regulator of cellular energy homeostasis. Activation of AMPK mimics the physiological state of fasting, promoting fat oxidation, suppressing lipogenesis, and inducing protective autophagy. Berberine (Berbevis phospholipid complex, 9.6x greater bioavailability) phosphorylates AMPK via LKB1 kinase and stimulates GLUT4 transporter translocation to skeletal muscle membranes, dramatically improving postprandial glucose clearance. Ceylon Cinnamon (10:1) provides type-A proanthocyanidins that inhibit intestinal alpha-glucosidase, reducing post-meal glycemic spikes. Chromium picolinate enhances insulin receptor phosphorylation, and R-Alpha Lipoic Acid regenerates antioxidant glutathione while improving mitochondrial glucose oxidation.

CLINICAL PRICE $59.00
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BIOCHEMICAL PATHWAY

Cellular Mechanism of Action

CLINICAL PHARMACOLOGICAL DOSSIER

Berberine phosphorylates AMPK via liver kinase B1 (LKB1), stimulating GLUT4 transporter translocation to skeletal muscle membrane.

EXTRACTION & PURITY SPECIFICATION:

Berberine HCl (Berbevis phospholipid matrix, 9.6x bioavailability), Cinnamomum Verum 10:1 water extract, Chromium Picolinate.

MOLECULAR STANDARDS
  • 100% Bio-Identical Structure
  • Zero Synthetic Fillers & Caffeine
  • cGMP European Certified Batch
  • Third-Party Heavy Metal Screened
CLINICALLY TOLERATED DAILY
STANDARDIZED BOTANICALS

Standardized Active Ingredients

Berbevis Berberine Phytosome Standardized Pure Fraction
550 mg
True Ceylon Cinnamon Extract Standardized Pure Fraction
200 mg
Chromium Picolinate Standardized Pure Fraction
200 mcg
Alpha Lipoic Acid (R-Form) Standardized Pure Fraction
150 mg
BIOMARKER IMPACT

Documented Clinical Benefits

Supports healthy fasting glucose and HbA1c in normal ranges
Activates cellular autophagy and fat oxidation pathways
Curbs sugar cravings and mid-afternoon energy crashes
Improves gut microbiome composition favoring Akkermansia muciniphila
DOSAGE & SAFETY

Clinical Usage Protocol

RECOMMENDED DOSAGE:

Take 1 capsule 15 minutes before your two largest carbohydrate-containing meals.

CONTRAINDICATIONS:

Concomitant use with antidiabetic sulfonylureas or insulin requires strict blood sugar titration to prevent hypoglycemia.

SAFETY GUIDELINE:

Discontinue use 2 weeks prior to scheduled surgical interventions.

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